Dr. Amy Killen is a board-certified physician and one of the most recognisable voices in regenerative and longevity medicine. She trained and worked for a decade as an emergency physician in Texas — until a burnt-out, sleep-deprived stretch made her rethink everything, and rebuild her life and her medicine around health rather than crisis.
Today, from Salt Lake City, she focuses on the parts of longevity others skip: hormones, stem cells and exosomes, skin, and sexual health. She and her partner pioneered the "Full Body Stem Cell Makeover," and she's known for a truth few in the field say out loud — that sexual health is a genuine marker of longevity.
She's a builder, too: co-founder of Humanaut Health (a longevity-clinic franchise aiming for 100 clinics), co-founder of the wearables-data app Reputable, and founder of a longevity supplement line. Her north star is access — making this medicine work for everyone, not just the wealthy.
And she keeps it human. She calls herself a "biohacker" and a "bioslacker" in the same breath, turned the hallmarks of aging into cartoon "Downfalls of Aging" characters, and still jumps on the trampoline with her kids. Do the basics, she says — and give yourself some slack.
Humanaut Health · Co-founderHormones · Stem cells · ExosomesSexual & skin healthFormer ER physician
Salt Lake City · Utah
Where we met
At her home in Salt Lake City
We visited Amy at her house in Salt Lake City — a long, sunlit conversation on the deck about hormones, stem cells, skin and sexual health, and why longevity has to reach everyone. Then we traded the cameras for mountain bikes and rode the Utah trails she moved here for.
Salt Lake City
Utah · her home
Where we filmed — on the deck with the mountains behind us, and stayed for dinner with her family.
On the trails
Mountain biking
We swapped interviews for bikes — the mountain in her backyard is the reason she moved to Utah.
Her mission
Longevity for all
Making regenerative medicine accessible — because "no one else is going to take care of you the way you can."
"As someone who has kids, this is a once-in-a-lifetime thing — treasure it."
— Amy Killen, at her home in Salt Lake City
On the quest
Moments with Amy
On the deckHer home in Salt Lake City, mountains behindWelcomed as familyShe had us to dinner with her family, Salt Lake CityOn the trailsMountain biking the Utah foothillsHer backyardThe mountain she moved to Utah forA great familyAmy & her daughter, Marek & Alek — sun at our backs, Utah
In her words
On longevity, hands-on
"Replacing hormones — especially the sex hormones — is the best thing you can do to live longer right now."
Amy Killen · Salt Lake City
Sexual health is the next level of health. There's a clear link between being sexually active and longevity — and almost no one's talking about it.
Amy Killen
Erectile dysfunction is the canary in the coal mine — you see it before the heart attack or the stroke.
Amy Killen
I'm a biohacker — but I'm also a bioslacker. I know what's good for me; I just don't always do it, and I'm okay with that.
Amy Killen
No one else is going to take care of you the way you can. You have to be the one who decides to be healthy.
Amy Killen
In his own words
Straight from the interview
Pulled from our conversation with Amy at her home in Salt Lake City — her science, how she lives it, and her message for the journey.
Amy's view on longevity
The parts others skip — hormones, sexual health, skin — are real levers on how long and how well you live.
"Replacing hormones is the best thing you can do to live longer right now."
Salt Lake City · 2024
How Amy does longevity
Basics first — sleep, movement, protein, play — plus rapamycin weekly and her own supplements, without being strict about it.
"I'm a biohacker — but also a bioslacker. I don't always do everything right, and I'm okay with that."
In her own life
Her message for the journey
Take longevity into your own hands — and treasure the time together while you can.
"No one else is going to take care of you the way you can — and treasure this time together."
The video interview is coming. Recorded interviews go live after the launch of the film & series Live Beyond.
Selected passages from our filmed conversation with Dr. Amy Killen — at her home in Salt Lake City.
On hormones as a longevity tool
Marek Piotrowski"Some people say we can do miracles with hormones; some say don't touch them."
Amy Killen"Outside of a healthy lifestyle, replacing hormones — especially the sex hormones — is the best thing you can do to live longer right now. In men, replacing testosterone lowers cardiovascular risk; in women, replacing estrogen early lowers heart disease, dementia and osteoporosis. There's a lot of misinformation out there, but when you start early, the data is strong."
On sexual health and longevity
Amy Killen"Sexual health is the next level of health. In one study, people who had sex at least once a week had a 50% lower all-cause mortality rate. And erectile dysfunction is the canary in the coal mine — you see it before the heart attack, because the blood vessels to the penis are smaller. It's a clear signal, and almost no one in longevity is talking about it."
On what stem cells really do
Amy Killen"Stem cells aren't a panacea, but they're incredible. We used to think you'd put them in a knee and they'd become cartilage. What we know now is they send signals — proteins, cytokines, extracellular vesicles — that wake up your own cells. That's why we can also use exosomes. They're understudied, mostly because no one will fund a trial on your own cells, but the benefit is real."
On being a biohacker — and a bioslacker
Marek Piotrowski"What does being a biohacker mean to you?"
Amy Killen"I say I'm a biohacker — but also a bioslacker. I love trying things and tracking the data, but I don't want to do everything right all the time; I want to enjoy a cookie with dinner. Sleep was the biggest change for me — when I left the ER and could sleep again, everything changed. Do the basics, and give yourself some slack."
On the ovary as the body's pacekeeper
Amy Killen"The ovaries are the pacekeepers of the body — they age two to five times faster than other organs, and once they give out at menopause, your hormones plummet and everything else speeds up: bones, blood vessels, brain. If we could delay ovarian aging even five or ten years, we'd give women another decade of health — without hormones."
Her message to the next generation
Aleksander Piotrowski"What's your message to the younger generation about longevity?"
Amy Killen"Be hopeful, and take good care of yourself now — because no one else is going to take care of you the way you can. There are no doctors out there who will keep you healthy long-term. If you really want it, you have to be the one who decides it."
More passages from the full interview will be published here.
Continue the quest
More minds on the quest
Amy Killen explores Biohacking Upgrades on the Longevity Map — here are others on the same frontier, and the full cast of 100+.
