Dane Gobel
Creating the MovementThe MovementPrizes, consortia and conferences — the scaffolding that turns scattered research into a field.
The Bridge · PreventionPreventionThe Biomarker of Aging Consortium — agreeing how we measure aging in the first place.
Live Beyond · A Great Mind on the Quest

Dane
Gobel

Methuselah Foundation · Biomarker of Aging Consortium
Prizes, NASA, and how we agree to measure aging · Virginia

Levels of Longevity Map Dane explores

Dane Gobel is one of 100+ experts in the Live Beyond Project — a father & son quest for longevity.

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NASA
Prize competition partner
100+
Things that go wrong — not one disease
~25 yrs
Of the field he grew up inside
Born
Not gestating — his verdict on the field
Who is Dane Gobel

The field just got its driver’s licence

Dane Gobel runs the Methuselah Foundation’s prize competitions — including a partnership with NASA — and works with the Biomarker of Aging Consortium, part of the group behind the Biomarkers of Aging conference at Harvard. He is also Dave Gobel’s son, which means he has spent most of his life inside a field that spent most of its life being laughed at.

That gives him an unusually long view. His verdict is that longevity research no longer feels like something gestating — it feels like something that has finally been born. His analogy is a teenager who has just passed their driving test: not yet an apartment in the city, but genuinely able to navigate the world.

He is careful about the framing everyone else fights over. He does not think aging is a disease. He thinks it is a hundred or more different things that can go wrong, conveniently bundled under one label — and that treating the label as a single target has been useful politically while remaining scientifically misleading.

He is also honest about where progress actually came from. The first ten years were brutal, though oddly low-risk, since everyone already assumed you were insane and any ground gained counted as a win. Regenerative medicine and 3D bioprinting made the field legible around 2010, because nobody objects to growing spare organs. The first gerotherapeutic startups followed in 2015 and 2016, and are only now reaching trials. And the first drug that genuinely moves healthspan at scale, he suspects, is a GLP-1 — which came from outside the longevity world entirely.

Methuselah prize competitions NASA partnership Biomarker of Aging Consortium Son of Dave Gobel
Portrait of Dane Gobel at the Biomarkers of Aging conference, Harvard 2024
Biomarkers of Aging · Harvard, 2024

Two fathers, two sons

Where we met

We met Dane twice: first in Virginia, on the same trip where we interviewed his father Dave, and again in Boston at the Biomarkers of Aging conference he helps organise. It was not lost on us. A father and son had travelled halfway around the world to interview a father and son who had built their working lives around the same question — one from the foundation and prize end, one from the measurement end.

Virginia
June 2024
At the family home — and Aleksander spent much of it talking with Dane.
Harvard
Biomarkers of Aging, 2024
The conference he helps run — on stage with the other organisers.
The prizes
Methuselah · NASA
Competitions designed to pull research forward rather than wait for it.

“It doesn’t feel so much like a field that’s gestating. It feels like a field that’s finally been born.”

— Dane Gobel, Virginia
In his words

Not one disease — a hundred things

“Personally, I don’t think aging is a disease. I think it’s about a hundred different things or more that can go wrong — nicely wrapped up in this label called aging.”

Dane Gobel · Methuselah Foundation

The first ten years were extraordinarily hard. In some ways easy, because the risk was so low — everyone already thought you were insane.

Dane Gobel

Nobody has any issue with generating organs from your own cells. Everyone would like to have more organs available.

Dane Gobel

The first real longevity drug is probably something like a GLP-1 — and that didn’t come out of the longevity community at all.

Dane Gobel

Biotech is already an extraordinarily risky space. It doesn’t make any sense to be in there. And it worked well enough.

Dane Gobel
In his own words

Straight from the interview

From our conversation in Virginia — the long view of a field he grew up inside, and where he thinks the real progress came from.

Why it feels different now

Startups founded in 2015 and 2016 are now entering or approaching clinical trials — and a biotech company usually needs a decade to get anywhere. What looked like stagnation was simply the length of the runway.

“Those early startups are on the cusp of doing it. It feels like it’s finally happening.”

Virginia · from the interview

What made it respectable

Not the audacious claims — the practical ones. Regenerative medicine and 3D bioprinting gave the field something nobody could object to, and that opened the door for the stranger, more ambitious work behind it.

“It’s so easy to get your head around. It’s so fundamental.”

Virginia · from the interview

The drug that came from outside

He is refreshingly unbothered that the most consequential healthspan drug so far didn’t emerge from his own field. Metformin is probably geroprotective, he says, but the effect isn’t close to what a GLP-1 does.

“That popped out of nowhere, and I’m very happy that it exists.”

Virginia · from the interview
Connect & follow

Explore Dane’s work

From the conversation

Dane Gobel, in his words

Video interview

The video interview is coming. Recorded interviews go live after the launch of the film & series Live Beyond.

Selected passages from our conversation with Dane Gobel — Virginia, June 2024. Lightly edited for readability.

On where the field is now

Dane Gobel“What excites me most is that it doesn’t feel so much like a field that’s gestating. It feels like a field that’s finally been born. Sometimes I compare it to a kid who’s got their driver’s licence — they might not have an apartment in the city yet, but they’re learning how to navigate the world. It’s a real thing.”

On whether aging is a disease

Dane Gobel“In the early 2000s people started thinking about how you could deal with aging as if it’s a disease. Personally, I don’t think it’s a disease. I think it’s about a hundred different things or more that can go wrong, which is nicely wrapped up in this label called aging.”

On the years when nobody believed it

Dane Gobel“The first ten years were extraordinarily hard. In some ways easy, because the risk was so low — everyone already thought you were insane. So if you could gain any ground, it was a win. You could do wild and crazy things. The stakes were low.”

On what actually opened the door

Dane Gobel“Around 2010 there was really good work in regenerative medicine and 3D bioprinting, which paved the way from a startup perspective for the more audacious things the gerotherapeutic world wanted to do. Nobody has any issue with generating organs from your own cells — everything is so practical. Everyone would like to have more organs available. Then in 2015, 2016, the first batch of gerotherapeutic startups really got going. All of that takes a lot of time. A biotech startup takes a decade to get something where it needs to go — and those early startups are now in trials or about to be. It feels like it’s finally happening. I’m incredibly grateful for everything the community did to keep going.”

On the first real longevity drug

Dane Gobel“I think the first longevity drug is probably something like Wegovy or Mounjaro, honestly. People have talked for years about metformin being geroprotective, and I think it probably is — but the effects are not nearly as profound as a GLP drug. And that didn’t come out of the longevity community. It popped out of nowhere, and I’m very happy that it exists. My hope is that the next round is the kind of thing that also dramatically increases longevity, almost passively.”

On whether he’d take a gene therapy himself

Marek Piotrowski“Would you take these gene therapies? Would you be ready to do that?”

Dane Gobel“I got invited to participate in a clinical trial for follistatin, and I’ve been talking with some folks about doing a Klotho trial. Personally I think it’s very interesting, and I’d probably do it. I’d want to dig into it further — but there’s a good chance I’d do it. I don’t have any personal objection to it at all. I think it’s cool.”

More passages from the full interview will be published here.

Continue the quest

More minds on the quest

Dane works across Creating the Movement and Prevention — the prizes that pull research forward, and the biomarkers that let us agree it worked. Start with his father, Dave.

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