Geriatrician & geroscientist · Universidad de Chile
Aging as a whole-life, whole-person process · Santiago
Levels of Longevity Map Felipe explores
Felipe Salech is one of 100+ experts in the Live Beyond Project — a father & son quest for longevity.
Discover Live Beyond →Felipe Salech is a geriatrician and geroscientist at the Universidad de Chile, and one of two Felipes who hosted the Chilean leg of the quest (the other is Felipe Court, a brain-ageing scientist — interviewed the same day). Salech co-founded Salud For Life and is a researcher at the GERO ageing centre in Santiago.
His starting point is a reframe. Gerontology is not only biology or medicine — it is the whole-person, whole-society study of ageing, reaching into economics and social science, because a human being is not divided into a biological part and an economic part. We age as one whole thing.
And ageing, he argues, is a whole-life process that must be addressed far earlier than the geriatric clinic. This is not theory for him: his group has biological data showing that children who grow up with obesity age faster — measured with biological clocks. The idea that you should tackle ageing while young now has hard evidence behind it.
The most useful thing he says is about how to actually motivate people — and it applies to everyone, not just the old. Nobody wants to see a geriatrician, because it is a symbol of getting old. So he does not sell youth; he sells a goal: independence. And to be independent you need two things, which frame his whole practice: a brain that can make your decisions, and a body that can carry them out.
Obesity, he points out, attacks both ends of that at once — raising the risk of dementia and stroke on the brain side, and infiltrating and inflaming the muscles on the body side, in a vicious cycle. Keep both working, for as long as possible, and you have kept the thing that actually matters.
Chile was not on many longevity maps, and that is part of why it mattered. Two Felipes invited father and son to Santiago — Salech the geriatrician, Court the brain-ageing scientist — and the university interviews are among the most grounded on the quest: no moonshots, just the unglamorous, rigorous business of measuring ageing and keeping people whole.
“To be independent you need two things: a brain that allows you to make your decisions, and a body that can carry your brain to reach them.”
— Felipe Salech, Santiago
“We have evidence that children who grow up with obesity have accelerated biological ageing — and we know it because we now have biological clocks to measure it.”
Felipe Salech · Universidad de Chile, April 2024Gerontology tries to understand ageing in a broad, comprehensive way — not only biology.
Felipe SalechWe are not a part biology and a part economics. We are a whole person.
Felipe SalechNobody wants to see a geriatrician — it’s a symbol of getting older. So we give them a goal.
Felipe SalechObesity attacks both: the brain that decides, and the body that moves.
Felipe SalechFrom the Santiago conversation — what geroscience changes, why he starts young, and how he actually talks to patients.
Geriatrics used to begin at 65 or 70. Geroscience moves the whole thing forward: if ageing is a life-long process, prevention belongs in childhood. His own research supplies the evidence — biological clocks showing that children who grow up obese are already ageing faster. The case for early action is no longer just intuitive.
“Facing ageing young is not only theoretical any more.”
Santiago · from the interviewHis answer to the hardest problem in the clinic: people avoid the geriatrician because it reminds them they are ageing, and you cannot simply tell someone to lose twenty kilos. So he reframes the whole thing around a goal everyone wants — staying independent — and works backwards from there.
“We transmit a goal: stay independent, as long as possible.”
Santiago · from the interviewIndependence, in his framing, has exactly two requirements: a brain that can still decide, and a body that can act on the decision. It is why obesity worries him so much — it damages both at once, dementia and stroke on one side, infiltrated and inflamed muscle on the other. Protect the pair, and you protect the person.
“A vicious cycle of inflammation, at both ends.”
Santiago · from the interviewFelipe Salech is a geriatrician at the Universidad de Chile and a researcher at GERO. Find him on LinkedIn.
The video interview is coming. Recorded interviews go live after the launch of the film & series Live Beyond.
From the conversation in Santiago, April 2024, at the Universidad de Chile. Lightly edited for readability.
Felipe Salech“Gerontology is the field dedicated to understanding ageing in humans — in a broad way. It’s not only biology, not only medicine. It tries to translate the knowledge for social science, for economics, for medicine, to have the most comprehensive view of ageing. Because ageing is part of our life, not only part of our biology. We are not a part biology and a part economics — we are a whole person.”
Felipe Salech“Gerontology used to work with older people — over 65, over 70. But geroscience tells us there’s a new way to approach ageing: as part of the whole life process. So it’s mandatory to begin at a very early stage of life. We have done studies showing that conditions like obesity change the way you age very early. Children who grow up with obesity have accelerated biological ageing in their bodies — and we know that because we now have technologies to assess biological age, using biological clocks. So the idea that you should face ageing while young is not only theoretical; we have biological data supporting it.”
Marek Piotrowski“You can’t just tell a patient to lose twenty kilos. How do you talk to them without hurting their feelings?”
Felipe Salech“We transmit them a goal. Older people don’t like to go to the geriatrician, because it’s a symbol of getting older. So the goal we give them is to stay independent, for as long as possible. And to be independent you need two main things: a brain that allows you to make your decisions, and a body that can carry your brain to reach them.”
Felipe Salech“If you have obesity, you have problems with both. On the brain: obesity increases the risk of dementia and stroke, and heart problems that affect the brain. On the body: obesity has a direct effect on the muscles — when you’re obese, it’s not only fat behind the skin, your muscles are infiltrated by fat, which produces negative effects.”
Marek Piotrowski“And inflammation, probably.”
Felipe Salech“Exactly — a vicious cycle of inflammation.”
More passages from the full interview will be published here.
Felipe Salech anchors The Bridge of Prevention (geroscience, biological age, early intervention) with a foot in Longevity Basics (the lifestyle roots of independence). Read him next to the other Felipe, Felipe Court.
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