CEO, Human Longevity (HLI)
Whole-genome prevention · San Diego
Levels of Longevity Map Wei-Wu explores
Wei-Wu He is one of 100+ experts in the Live Beyond Project — a father & son quest for longevity.
Discover Live Beyond →Wei-Wu He is the CEO of Human Longevity (HLI) in San Diego — a precision-medicine longevity clinic that reads your whole genome and images your whole body to find disease long before symptoms appear. It sits squarely on the Bridge of Prevention: the whole point is to catch what’s coming while it can still be changed. (It’s one of the four clinics in our Clinics directory, too.)
His interest in longevity is lifelong, and painfully personal. Growing up in China, he was six or seven when his grandmother was diagnosed with late-stage cervical cancer — from diagnosis to death was about two months. That early loss shaped a life. He studied biochemistry under a professor who lived to 110, and who encouraged him to come to the US for his PhD (Baylor, Mayo Clinic, Mass General).
Then, in 1993, a turning point: he met Craig Venter, who recruited him to help start Human Genome Sciences — the first large-scale DNA-sequencing company on Earth. Decades later, when Venter founded Human Longevity, Wei-Wu joined as an investor and board member, and eventually took the helm as CEO.
His conviction is simple and vast: “We have finally decoded our genome — the operating software of the human body.” Longevity, to him, is now a data-driven science. Read the code, measure the body, and you can move medicine from reacting to disease toward preventing it. We interviewed his daughter, Christine, on the same visit — a father and a daughter, both in the mission.
We met Wei-Wu on the lawn at Human Longevity in San Diego — Craig Venter’s plane visible overhead, he joked. He is a genomics pioneer who has watched the whole field grow from the first sequencing machines to a clinic that can read your entire genome in an afternoon. He speaks about it with the calm of someone who has been certain for thirty years that this is where medicine was always heading. We also met his daughter Christine that day.
“We human beings have reached a point where we finally decoded our genome — because that is the operating software of our human body.”
— Wei-Wu He, San Diego
“It’s a data-driven science. If you look at the last 150 years, there’s been so much revolution in human health that we’ve extended our lifespan — and the genome is the next chapter.”
Wei-Wu He · Human LongevityI’ve been interested in longevity for as long as I’ve been on Earth.
Wei-Wu HeMy professor in China is the oldest living professor — he lived to 110.
Wei-Wu HeIn ’93 I met Craig, and he recruited me to start Human Genome Sciences — the first large-scale DNA-sequencing company on Earth.
Wei-Wu HeWe finally decoded our genome, because that’s the operating software of our human body.
Wei-Wu HeThree threads that made him.
A grandmother lost to cancer in two months when he was a child. That grief became a lifelong pull toward catching disease earlier — the emotional root of a career spent on prevention.
“From diagnosis to death was two months.”
San Diego · from the interviewRecruited by Craig Venter in 1993 to help build the first large-scale DNA-sequencing company. He didn’t read about the genomics revolution — he helped start it, and has carried it into the clinic.
“The first sequencing company on Earth.”
San Diego · from the interviewHLI’s bet: your genome is the body’s operating software, and your scans are its live diagnostics. Combine them and medicine shifts from treating disease to preventing it — the Bridge, made real.
“The operating software of the body.”
San Diego · from the interviewWei-Wu He is CEO of Human Longevity (humanlongevity.com) in San Diego. His daughter Christine was also part of the quest.
The video interview is coming. Recorded interviews go live after the launch of the film & series Live Beyond.
Wei-Wu He was filmed on the lawn at Human Longevity, San Diego, 2024. Passages from that conversation:
Wei-Wu He“I’ve been interested in longevity for as long as I’ve been on Earth. I grew up in China with my grandmother, and around when I was six or seven she was diagnosed with late-stage cervical cancer — from diagnosis to her death was about two months. That has a lot to do with it. I studied biochemistry in China; my professor is the oldest living professor — he lived to 110 — and he encouraged me to come to the US for my PhD.”
Wei-Wu He“In ’93, serendipitously, I met Craig, and he recruited me to start his first company, Human Genome Sciences — literally the first large-scale DNA-sequencing company on Earth. In 2015 a friend told me Craig was starting Human Longevity. I became an investor, joined the board, and eventually became CEO.”
Wei-Wu He“We human beings have reached a point where we finally decoded our genome — because that is the operating software of our human body. It’s a data-driven science. If you look at the last 150 years, there’s been so much revolution in human health that we’ve extended our lifespan. The genome is the next chapter.”
More passages from the full interview will be published here.
Wei-Wu He sits on the Bridge of Prevention on the Longevity Map. Explore the rest of the cast on the People page.
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