
Altered intercellular communication
Cells stop talking properly
A body is an organisation of forty trillion members, and it only works because they keep each other informed — by hormone, by immune signal, by nerve. With age the messages get noisier and the departments stop hearing one another. Each starts optimising for itself, which is exactly how an organisation fails.
This is where Kroemer’s point does the work: everything is connected, so improving any other entry on this page improves this one too. Directly, the levers are sleep, daylight early in the day, and keeping the background burn of number eleven down.
The science, in one sentence
The signalling between cells and between organs — hormonal, immune, neuronal — becomes noisier and less coordinated.